Yes, it is normal to have soreness or discomfort at the injection site after your procedure. Common symptoms after an injection includes sore, ache, or stiff. Everybody experiences pain differently. To decrease discomfort, apply ice packs 15 minutes every hour, for 24 hours while you’re awake. DO NOT use heat for 2-3 days after your injection. You may take over the counter medicines like Tylenol, Motrin or Aleve for inflammation and pain if needed. Call the office if you experience any of the symptoms listed: fever over 101° F, severe headache, severe nausea and vomiting, discomfort that becomes severe or interferes with normal movement that you have never had before.